Induction of gut regulatory CD39(+) T cells by teriflunomide protects against EAE

OBJECTIVE: To determine whether as an orally delivered treatment, teriflunomide, an inhibitor of the mitochondrial enzyme dihydroorotate dehydrogenase approved to treat relapsing forms of multiple sclerosis, could affect gut-associated lymphoid tissue (GALT) immune responses functionally. METHODS: C...

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Detalles Bibliográficos
Autores principales: Ochoa-Repáraz, Javier, Colpitts, Sara L., Kircher, Christopher, Kasper, Eli J., Telesford, Kiel M., Begum-Haque, Sakhina, Pant, Anudeep, Kasper, Lloyd H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063394/
https://www.ncbi.nlm.nih.gov/pubmed/27766282
http://dx.doi.org/10.1212/NXI.0000000000000291

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063394/
https://www.ncbi.nlm.nih.gov/pubmed/27766282
http://dx.doi.org/10.1212/NXI.0000000000000291

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