Targeting bortezomib-induced aggresome formation using vinorelbine enhances the cytotoxic effect along with ER stress loading in breast cancer cell lines

The ubiquitin-proteasome and autophagy-lysosome pathways are two major self-digestive systems for cellular proteins. Ubiquitinated misfolded proteins are degraded mostly by proteasome. However, when ubiquitinated proteins accumulate beyond the capacity of proteasome clearance, they are transported t...

Descripción completa

Detalles Bibliográficos
Autores principales: Miyahara, Kana, Kazama, Hiromi, Kokuba, Hiroko, Komatsu, Seiichiro, Hirota, Ayako, Takemura, Jun, Hirasawa, Kazuhiro, Moriya, Shota, Abe, Akihisa, Hiramoto, Masaki, Ishikawa, Takashi, Miyazawa, Keisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063435/
https://www.ncbi.nlm.nih.gov/pubmed/27601063
http://dx.doi.org/10.3892/ijo.2016.3673

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063435/
https://www.ncbi.nlm.nih.gov/pubmed/27601063
http://dx.doi.org/10.3892/ijo.2016.3673

Ejemplares similares