CpxR Activates MexAB-OprM Efflux Pump Expression and Enhances Antibiotic Resistance in Both Laboratory and Clinical nalB-Type Isolates of Pseudomonas aeruginosa

Resistance-Nodulation-Division (RND) efflux pumps are responsible for multidrug resistance in Pseudomonas aeruginosa. In this study, we demonstrate that CpxR, previously identified as a regulator of the cell envelope stress response in Escherichia coli, is directly involved in activation of expressi...

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Detalles Bibliográficos
Autores principales: Tian, Zhe-Xian, Yi, Xue-Xian, Cho, Anna, O’Gara, Fergal, Wang, Yi-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063474/
https://www.ncbi.nlm.nih.gov/pubmed/27736975
http://dx.doi.org/10.1371/journal.ppat.1005932

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063474/
https://www.ncbi.nlm.nih.gov/pubmed/27736975
http://dx.doi.org/10.1371/journal.ppat.1005932

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