Cross-Linking GPVI-Fc by Anti-Fc Antibodies Potentiates Its Inhibition of Atherosclerotic Plaque- and Collagen-Induced Platelet Activation

To enhance the antithrombotic properties of recombinant glycoprotein VI fragment crystallizable (GPVI-Fc), the authors incubated GPVI-Fc with anti-human Fc antibodies to cross-link the Fc tails of GPVI-Fc. Cross-linking potentiated the inhibition of human plaque- and collagen-induced platelet aggreg...

Descripción completa

Detalles Bibliográficos
Autores principales: Jamasbi, Janina, Megens, Remco T.A., Bianchini, Mariaelvy, Uhland, Kerstin, Münch, Götz, Ungerer, Martin, Sherman, Shachar, Faussner, Alexander, Brandl, Richard, John, Christine, Buchner, Johannes, Weber, Christian, Lorenz, Reinhard, Elia, Natalie, Siess, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
PRE-CLINICAL RESEARCH
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063538/
https://www.ncbi.nlm.nih.gov/pubmed/27766315
http://dx.doi.org/10.1016/j.jacbts.2016.03.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063538/
https://www.ncbi.nlm.nih.gov/pubmed/27766315
http://dx.doi.org/10.1016/j.jacbts.2016.03.008

Ejemplares similares