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The Kynurenine Pathway Is a Double-Edged Sword in Immune-Privileged Sites and in Cancer: Implications for Immunotherapy

The term “immune privilege” was originally coined to describe the suppression of inflammatory responses within organs protected by anatomic barriers, ie, the eyes, brain, placenta, and testes. However, cellular and metabolic processes, which orchestrate immune responses, also control inflammation wi...

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Detalles Bibliográficos
Autores principales: Routy, Jean-Pierre, Routy, Bertrand, Graziani, Gina M., Mehraj, Vikram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063567/
https://www.ncbi.nlm.nih.gov/pubmed/27773992
http://dx.doi.org/10.4137/IJTR.S38355