Pretreatment with a γ-Secretase Inhibitor Prevents Tumor-like Overgrowth in Human iPSC-Derived Transplants for Spinal Cord Injury

Neural stem/progenitor cells (NS/PCs) derived from human induced pluripotent stem cells (hiPSCs) are considered to be a promising cell source for cell-based interventions that target CNS disorders. We previously reported that transplanting certain hiPSC-NS/PCs in the spinal cord results in tumor-lik...

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Detalles Bibliográficos
Autores principales: Okubo, Toshiki, Iwanami, Akio, Kohyama, Jun, Itakura, Go, Kawabata, Soya, Nishiyama, Yuichiro, Sugai, Keiko, Ozaki, Masahiro, Iida, Tsuyoshi, Matsubayashi, Kohei, Matsumoto, Morio, Nakamura, Masaya, Okano, Hideyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063571/
https://www.ncbi.nlm.nih.gov/pubmed/27666789
http://dx.doi.org/10.1016/j.stemcr.2016.08.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063571/
https://www.ncbi.nlm.nih.gov/pubmed/27666789
http://dx.doi.org/10.1016/j.stemcr.2016.08.015

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