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Pretreatment with a γ-Secretase Inhibitor Prevents Tumor-like Overgrowth in Human iPSC-Derived Transplants for Spinal Cord Injury
Neural stem/progenitor cells (NS/PCs) derived from human induced pluripotent stem cells (hiPSCs) are considered to be a promising cell source for cell-based interventions that target CNS disorders. We previously reported that transplanting certain hiPSC-NS/PCs in the spinal cord results in tumor-lik...
Autores principales: | Okubo, Toshiki, Iwanami, Akio, Kohyama, Jun, Itakura, Go, Kawabata, Soya, Nishiyama, Yuichiro, Sugai, Keiko, Ozaki, Masahiro, Iida, Tsuyoshi, Matsubayashi, Kohei, Matsumoto, Morio, Nakamura, Masaya, Okano, Hideyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063571/ https://www.ncbi.nlm.nih.gov/pubmed/27666789 http://dx.doi.org/10.1016/j.stemcr.2016.08.015 |
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