Mouse genetic background contributes to hepatocyte susceptibility to Fas-mediated apoptosis

Liver disease progression is modulated by genetic modifiers in mouse strains and across human races and ethnicities. We hypothesized that hepatocyte culture duration and genetic background regulate hepatocyte susceptibility to apoptosis. Hepatocytes were isolated from FVB/N, C57BL/6, and C3H/He mice...

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Detalles Bibliográficos
Autores principales: Weerasinghe, Sujith V. W., Park, Min-Jung, Portney, Daniel A., Omary, M. Bishr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063609/
https://www.ncbi.nlm.nih.gov/pubmed/27535425
http://dx.doi.org/10.1091/mbc.E15-06-0423

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063609/
https://www.ncbi.nlm.nih.gov/pubmed/27535425
http://dx.doi.org/10.1091/mbc.E15-06-0423

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