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Mena(INV) mediates synergistic cross-talk between signaling pathways driving chemotaxis and haptotaxis

Directed cell migration, a key process in metastasis, arises from the combined influence of multiple processes, including chemotaxis—the directional movement of cells to soluble cues—and haptotaxis—the migration of cells on gradients of substrate-bound factors. However, it is unclear how chemotactic...

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Detalles Bibliográficos
Autores principales: Oudin, Madeleine J., Miller, Miles A., Klazen, Joelle A. Z., Kosciuk, Tatsiana, Lussiez, Alisha, Hughes, Shannon K., Tadros, Jenny, Bear, James E., Lauffenburger, Douglas A., Gertler, Frank B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063616/
https://www.ncbi.nlm.nih.gov/pubmed/27559126
http://dx.doi.org/10.1091/mbc.E16-04-0212