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Actin filaments as dynamic reservoirs for Drp1 recruitment

Drp1 is a dynamin-family GTPase recruited to mitochondria and peroxisomes, where it oligomerizes and drives membrane fission. Regulation of mitochondrial Drp1 recruitment is not fully understood. We previously showed that Drp1 binds actin filaments directly, and actin polymerization is necessary for...

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Detalles Bibliográficos
Autores principales: Hatch, Anna L., Ji, Wei-Ke, Merrill, Ronald A., Strack, Stefan, Higgs, Henry N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063618/
https://www.ncbi.nlm.nih.gov/pubmed/27559132
http://dx.doi.org/10.1091/mbc.E16-03-0193