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Assembly of Caenorhabditis elegans acentrosomal spindles occurs without evident microtubule-organizing centers and requires microtubule sorting by KLP-18/kinesin-12 and MESP-1

Although centrosomes contribute to spindle formation in most cell types, oocytes of many species are acentrosomal and must organize spindles in their absence. Here we investigate this process in Caenorhabditis elegans, detailing how acentrosomal spindles form and revealing mechanisms required to est...

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Detalles Bibliográficos
Autores principales: Wolff, Ian D., Tran, Michael V., Mullen, Timothy J., Villeneuve, Anne M., Wignall, Sarah M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063619/
https://www.ncbi.nlm.nih.gov/pubmed/27559133
http://dx.doi.org/10.1091/mbc.E16-05-0291