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Data on the purification and crystallization of the loss-of-function von Willebrand disease variant (p.Gly1324Ser) of the von Willebrand factor A1 domain

von Willebrand factor׳s (VWF) primary hemostatic responsibility is to deposit platelets at sites of vascular injury to prevent bleeding. This function is mediated by the interaction between the VWF A1 domain and the constitutively active platelet receptor, GPIbα. The crystal structure of the A1 doma...

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Detalles Bibliográficos
Autores principales: Campbell, James C., Tischer, Alexander, Machha, Venkata, Moon-Tasson, Laurie, Sankaran, Banumathi, Kim, Choel, Auton, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063811/
https://www.ncbi.nlm.nih.gov/pubmed/27761512
http://dx.doi.org/10.1016/j.dib.2016.05.004