Cargando…
Design and synthesis of chalcone derivatives as potential non-purine xanthine oxidase inhibitors
BACKGROUND: Based on some previous research, the chalcone derivatives exhibited potent xanthine oxidase inhibitory activity, e.g. sappanchalcone (7), with IC(50) value of 3.9 μM, was isolated from Caesalpinia sappan. Therefore, objectives of this research are design and synthesis of 7 and other chal...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063830/ https://www.ncbi.nlm.nih.gov/pubmed/27795931 http://dx.doi.org/10.1186/s40064-016-3485-6 |