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Stat6-Dependent Inhibition of Mincle Expression in Mouse and Human Antigen-Presenting Cells by the Th2 Cytokine IL-4

The C-type lectin receptors (CLRs) Mincle, Mcl, and Dectin-2 bind mycobacterial and fungal cell wall glycolipids and carbohydrates. Recently, we described that expression of these CLR is downregulated during differentiation of human monocytes to dendritic cells (DC) in the presence of GM-CSF and IL-...

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Detalles Bibliográficos
Autores principales: Hupfer, Thomas, Schick, Judith, Jozefowski, Katrin, Voehringer, David, Ostrop, Jenny, Lang, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063851/
https://www.ncbi.nlm.nih.gov/pubmed/27790218
http://dx.doi.org/10.3389/fimmu.2016.00423