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Localized force application reveals mechanically sensitive domains of Piezo1

Piezos are mechanically activated ion channels that function as sensors of touch and pressure in various cell types. However, the precise mechanism and structures mediating mechanical activation and subsequent inactivation have not yet been identified. Here we use magnetic nanoparticles as localized...

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Detalles Bibliográficos
Autores principales: Wu, Jason, Goyal, Raman, Grandl, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063965/
https://www.ncbi.nlm.nih.gov/pubmed/27694883
http://dx.doi.org/10.1038/ncomms12939