Comprehensive functional analysis of the tousled-like kinase 2 frequently amplified in aggressive luminal breast cancers

More aggressive and therapy-resistant oestrogen receptor (ER)-positive breast cancers remain a great clinical challenge. Here our integrative genomic analysis identifies tousled-like kinase 2 (TLK2) as a candidate kinase target frequently amplified in ∼10.5% of ER-positive breast tumours. The result...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Jin-Ah, Tan, Ying, Wang, Xian, Cao, Xixi, Veeraraghavan, Jamunarani, Liang, Yulong, Edwards, Dean P., Huang, Shixia, Pan, Xuewen, Li, Kaiyi, Schiff, Rachel, Wang, Xiao-Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064015/
https://www.ncbi.nlm.nih.gov/pubmed/27694828
http://dx.doi.org/10.1038/ncomms12991

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064015/
https://www.ncbi.nlm.nih.gov/pubmed/27694828
http://dx.doi.org/10.1038/ncomms12991

Ejemplares similares