Specification of haematopoietic stem cell fate via modulation of mitochondrial activity

Haematopoietic stem cells (HSCs) differ from their committed progeny by relying primarily on anaerobic glycolysis rather than mitochondrial oxidative phosphorylation for energy production. However, whether this change in the metabolic program is the cause or the consequence of the unique function of...

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Detalles Bibliográficos
Autores principales: Vannini, Nicola, Girotra, Mukul, Naveiras, Olaia, Nikitin, Gennady, Campos, Vasco, Giger, Sonja, Roch, Aline, Auwerx, Johan, Lutolf, Matthias P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064016/
https://www.ncbi.nlm.nih.gov/pubmed/27731316
http://dx.doi.org/10.1038/ncomms13125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064016/
https://www.ncbi.nlm.nih.gov/pubmed/27731316
http://dx.doi.org/10.1038/ncomms13125

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