Cargando…

Specification of haematopoietic stem cell fate via modulation of mitochondrial activity

Haematopoietic stem cells (HSCs) differ from their committed progeny by relying primarily on anaerobic glycolysis rather than mitochondrial oxidative phosphorylation for energy production. However, whether this change in the metabolic program is the cause or the consequence of the unique function of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vannini, Nicola, Girotra, Mukul, Naveiras, Olaia, Nikitin, Gennady, Campos, Vasco, Giger, Sonja, Roch, Aline, Auwerx, Johan, Lutolf, Matthias P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064016/ https://www.ncbi.nlm.nih.gov/pubmed/27731316 http://dx.doi.org/10.1038/ncomms13125

Ejemplares similares

Single-cell analyses identify bioengineered niches for enhanced maintenance of hematopoietic stem cells
por: Roch, Aline, et al.
Publicado: (2017)

Targeting mitochondria to stimulate hematopoiesis
por: Girotra, Mukul, et al.
Publicado: (2020)

In Vivo Pre-Instructed HSCs Robustly Execute Asymmetric Cell Divisions In Vitro
por: Girotra, Mukul, et al.
Publicado: (2020)

P1400: BOOSTING MITOCHONDRIAL RECYCLING REJUVENATES HEMATOPOIETIC AND IMMUNE SYSTEMS
por: Chiang, Y.-H., et al.
Publicado: (2022)

High-throughput, nonperturbing quantification of lipid droplets with digital holographic microscopy
por: Campos, Vasco, et al.
Publicado: (2018)

Corrigendum: High-throughput, nonperturbing quantification of lipid droplets with digital holographic microscopy
por: Campos, Vasco, et al.
Publicado: (2022)

Gastruloids as in vitro models of embryonic blood development with spatial and temporal resolution
por: Rossi, Giuliana, et al.
Publicado: (2022)

PU.1 and Haematopoietic Cell Fate: Dosage Matters
por: Mak, Ka Sin, et al.
Publicado: (2011)

Multiscale microenvironmental perturbation of pluripotent stem cell fate and self-organization
por: Tabata, Yoji, et al.
Publicado: (2017)

Smart Hydrogels for the Augmentation of Bone Regeneration by Endogenous Mesenchymal Progenitor Cell Recruitment
por: Lienemann, Philipp S., et al.
Publicado: (2020)

Repression of arterial genes in hemogenic endothelium is sufficient for haematopoietic fate acquisition
por: Lizama, Carlos O., et al.
Publicado: (2015)

Polylox barcoding reveals haematopoietic stem cell fates realized in vivo
por: Pei, Weike, et al.
Publicado: (2017)

PU.1 and partners: regulation of haematopoietic stem cell fate in normal and malignant haematopoiesis
por: Gupta, Pallavi, et al.
Publicado: (2009)

Medial HOXA genes demarcate haematopoietic stem cell fate during human development
por: Dou, Diana R., et al.
Publicado: (2016)

Brief Report From the 3rd International Meeting on Bone Marrow Adiposity (BMA 2017)
por: Corsi, Alessandro, et al.
Publicado: (2019)

Raman microspectroscopy reveals unsaturation heterogeneity at the lipid droplet level and validates an in vitro model of bone marrow adipocyte subtypes
por: Tratwal, Josefine, et al.
Publicado: (2022)

Differential Blood Counts Do Not Consistently Predict Clinical Measurements of Bone Mineral Density and Microarchitecture at Homeostasis
por: Schyrr, Frederica, et al.
Publicado: (2022)

The mitochondrial respiratory chain is essential for haematopoietic stem cell function
por: Ansó, Elena, et al.
Publicado: (2017)

Mineral and Amino Acid Profiling of Different Hematopoietic Populations from the Mouse Bone Marrow
por: Girotra, Mukul, et al.
Publicado: (2020)

Bone marrow adipocytes as negative regulators of the hematopoietic microenvironment
por: Naveiras, Olaia, et al.
Publicado: (2009)

Prevention and management of carbapenem-resistant Enterobacteriaceae in haematopoietic cell transplantation
por: Sahitya, Dangudubiyyam Sri Krishna, et al.
Publicado: (2021)

3D niche microarrays for systems-level analyses of cell fate
por: Ranga, A., et al.
Publicado: (2014)

The Birth of the Eye Vesicle: When Fate Decision Equals Morphogenesis
por: Giger, Florence A., et al.
Publicado: (2018)

Correlation study between osteoporosis and hematopoiesis in the context of adjuvant chemotherapy for breast cancer
por: Schyrr, Frédérica, et al.
Publicado: (2017)

Transcriptional regulation of haematopoietic transcription factors
por: Wilson, Nicola K, et al.
Publicado: (2011)

Jam1a – Jam2a interactions regulate haematopoietic stem cell fate through Notch signalling
por: Kobayashi, Isao, et al.
Publicado: (2014)

A Single Metabolite which Modulates Lipid Metabolism Alters Hematopoietic Stem/Progenitor Cell Behavior and Promotes Lymphoid Reconstitution
por: Giger, Sonja, et al.
Publicado: (2020)

Recapitulative haematopoietic development of human pluripotent stem cells in the absence of exogenous haematopoietic cytokines
por: Philonenko, Elena S., et al.
Publicado: (2021)

Heterotrimeric kinesin-II is necessary and sufficient to promote different stepwise assembly of morphologically distinct bipartite cilia in Drosophila antenna
por: Jana, Swadhin C., et al.
Publicado: (2011)

The WHO's who of haematopoietic malignancies
por: Oram, S H, et al.
Publicado: (2009)

Microarrayed human bone marrow organoids for modeling blood stem cell dynamics
por: Giger, Sonja, et al.
Publicado: (2022)

The Haematopoietic Stem Cell Niche: New Insights into the Mechanisms Regulating Haematopoietic Stem Cell Behaviour
por: Lilly, Andrew J., et al.
Publicado: (2011)

Bone marrow adipocytes promote the regeneration of stem cells and hematopoiesis by secreting SCF
por: Zhou, Bo O., et al.
Publicado: (2017)

Mitophagy, Mitochondrial Homeostasis, and Cell Fate
por: Ma, Kaili, et al.
Publicado: (2020)

Editorial: Mitochondrial control of cell fate
por: Gong, Guohua, et al.
Publicado: (2023)

Epigenetic Changes as a Target in Aging Haematopoietic Stem Cells and Age-Related Malignancies
por: Buisman, Sonja C., et al.
Publicado: (2019)

Plasmodium asexual growth and sexual development in the haematopoietic niche of the host
por: Venugopal, Kannan, et al.
Publicado: (2020)

Expansion of Haematopoietic Stem and Progenitor Cells: Paving the Way for Next-Generation Haematopoietic Stem Cell Transplantation
por: Bari, Sudipto, et al.
Publicado: (2019)

Vitronectin‐activated αvβ3 and αvβ5 integrin signalling specifies haematopoietic fate in human pluripotent stem cells
por: Shen, Jun, et al.
Publicado: (2021)

Standardizing haematopoietic cell transplants in China
por: Gale, Robert Peter
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_qgo1jts7l9rh7uke2qo1i5nald