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Specification of haematopoietic stem cell fate via modulation of mitochondrial activity
Haematopoietic stem cells (HSCs) differ from their committed progeny by relying primarily on anaerobic glycolysis rather than mitochondrial oxidative phosphorylation for energy production. However, whether this change in the metabolic program is the cause or the consequence of the unique function of...
Autores principales: | Vannini, Nicola, Girotra, Mukul, Naveiras, Olaia, Nikitin, Gennady, Campos, Vasco, Giger, Sonja, Roch, Aline, Auwerx, Johan, Lutolf, Matthias P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064016/ https://www.ncbi.nlm.nih.gov/pubmed/27731316 http://dx.doi.org/10.1038/ncomms13125 |
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