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Polarization of M2 macrophages requires Lamtor1 that integrates cytokine and amino-acid signals

Macrophages play crucial roles in host defence and tissue homoeostasis, processes in which both environmental stimuli and intracellularly generated metabolites influence activation of macrophages. Activated macrophages are classified into M1 and M2 macrophages. It remains unclear how intracellular n...

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Detalles Bibliográficos
Autores principales: Kimura, Tetsuya, Nada, Shigeyuki, Takegahara, Noriko, Okuno, Tatsusada, Nojima, Satoshi, Kang, Sujin, Ito, Daisuke, Morimoto, Keiko, Hosokawa, Takashi, Hayama, Yoshitomo, Mitsui, Yuichi, Sakurai, Natsuki, Sarashina-Kida, Hana, Nishide, Masayuki, Maeda, Yohei, Takamatsu, Hyota, Okuzaki, Daisuke, Yamada, Masaki, Okada, Masato, Kumanogoh, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064021/
https://www.ncbi.nlm.nih.gov/pubmed/27731330
http://dx.doi.org/10.1038/ncomms13130