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Leucine‐rich repeat containing protein LRRC8A is essential for swelling‐activated Cl(−) currents and embryonic development in zebrafish

A volume‐regulated anion channel (VRAC) has been electrophysiologically characterized in innumerable mammalian cell types. VRAC is activated by cell swelling and mediates the volume regulatory efflux of Cl(−) and small organic solutes from cells. Two groups recently identified the mammalian leucine‐...

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Detalles Bibliográficos
Autores principales: Yamada, Toshiki, Wondergem, Robert, Morrison, Rebecca, Yin, Viravuth P., Strange, Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064130/
https://www.ncbi.nlm.nih.gov/pubmed/27688432
http://dx.doi.org/10.14814/phy2.12940