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Leucine‐rich repeat containing protein LRRC8A is essential for swelling‐activated Cl(−) currents and embryonic development in zebrafish
A volume‐regulated anion channel (VRAC) has been electrophysiologically characterized in innumerable mammalian cell types. VRAC is activated by cell swelling and mediates the volume regulatory efflux of Cl(−) and small organic solutes from cells. Two groups recently identified the mammalian leucine‐...
Autores principales: | Yamada, Toshiki, Wondergem, Robert, Morrison, Rebecca, Yin, Viravuth P., Strange, Kevin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064130/ https://www.ncbi.nlm.nih.gov/pubmed/27688432 http://dx.doi.org/10.14814/phy2.12940 |
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