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Induction of Interleukin-22 (IL-22) production in CD4(+) T Cells by IL-17A Secreted from CpG-Stimulated Keratinocytes

BACKGROUND: Interleukin-17A (IL-17A) is mainly secreted from Th17 cells that are activated by various stimuli including CpG oligodeoxynucleotide, a Toll-like receptor 9 (TLR9) ligand. Recently, it has been demonstrated that keratinocytes play an important role in the pathogenesis of psoriasis. OBJEC...

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Detalles Bibliográficos
Autores principales: Li, Zheng Jun, Choi, Dae-Kyoung, Sohn, Kyung-Cheol, Lim, Seul Ki, Im, Myung, Lee, Young, Seo, Young-Joon, Kim, Chang Deok, Lee, Jeung-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Dermatological Association; The Korean Society for Investigative Dermatology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064187/
https://www.ncbi.nlm.nih.gov/pubmed/27746637
http://dx.doi.org/10.5021/ad.2016.28.5.579