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Smooth muscle cell-specific Tgfbr1 deficiency promotes aortic aneurysm formation by stimulating multiple signaling events

Transforming growth factor (TGF)-β signaling disorder has emerged as a common molecular signature for aortic aneurysm development. The timing of postnatal maturation plays a key role in dictating the biological outcome of TGF-β signaling disorders in the aortic wall. In this study, we investigated t...

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Detalles Bibliográficos
Autores principales: Yang, Pu, Schmit, Bradley M., Fu, Chunhua, DeSart, Kenneth, Oh, S. Paul, Berceli, Scott A., Jiang, Zhihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064316/
https://www.ncbi.nlm.nih.gov/pubmed/27739498
http://dx.doi.org/10.1038/srep35444