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Smooth muscle cell-specific Tgfbr1 deficiency promotes aortic aneurysm formation by stimulating multiple signaling events
Transforming growth factor (TGF)-β signaling disorder has emerged as a common molecular signature for aortic aneurysm development. The timing of postnatal maturation plays a key role in dictating the biological outcome of TGF-β signaling disorders in the aortic wall. In this study, we investigated t...
Autores principales: | Yang, Pu, Schmit, Bradley M., Fu, Chunhua, DeSart, Kenneth, Oh, S. Paul, Berceli, Scott A., Jiang, Zhihua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064316/ https://www.ncbi.nlm.nih.gov/pubmed/27739498 http://dx.doi.org/10.1038/srep35444 |
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