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S. aureus blocks efferocytosis of neutrophils by macrophages through the activity of its virulence factor alpha toxin
Bacterial pneumonia, such as those caused by Staphylococcus aureus, is associated with an influx of inflammatory neutrophils into the lung tissue and airways. Regulation and clearance of recruited neutrophils is essential for preventing tissue damage by “friendly fire”, a responsibility of macrophag...
Autores principales: | Cohen, Taylor S., Jones-Nelson, Omari, Hotz, Meghan, Cheng, Lily, Miller, Lloyd S., Suzich, JoAnn, Stover, C. Kendall, Sellman, Bret R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064327/ https://www.ncbi.nlm.nih.gov/pubmed/27739519 http://dx.doi.org/10.1038/srep35466 |
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