Decrease in pH destabilizes individual vault nanocages by weakening the inter-protein lateral interaction

Vault particles are naturally occurring proteinaceous cages with promising application as molecular containers. The use of vaults as functional transporters requires a profound understanding of their structural stability to guarantee the protection and controlled payload delivery. Previous results p...

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Detalles Bibliográficos
Autores principales: Llauró, Aida, Guerra, Pablo, Kant, Ravi, Bothner, Brian, Verdaguer, Núria, de Pablo, Pedro J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064368/
https://www.ncbi.nlm.nih.gov/pubmed/27739422
http://dx.doi.org/10.1038/srep34143

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064368/
https://www.ncbi.nlm.nih.gov/pubmed/27739422
http://dx.doi.org/10.1038/srep34143

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