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Decrease in pH destabilizes individual vault nanocages by weakening the inter-protein lateral interaction
Vault particles are naturally occurring proteinaceous cages with promising application as molecular containers. The use of vaults as functional transporters requires a profound understanding of their structural stability to guarantee the protection and controlled payload delivery. Previous results p...
Autores principales: | Llauró, Aida, Guerra, Pablo, Kant, Ravi, Bothner, Brian, Verdaguer, Núria, de Pablo, Pedro J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064368/ https://www.ncbi.nlm.nih.gov/pubmed/27739422 http://dx.doi.org/10.1038/srep34143 |
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