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Non-random pairing of CD46 isoforms with skewing towards BC2 and C2 in activated and memory/effector T cells

CD46 is a glycoprotein with important functions in innate and adaptive immune responses. Functionally different isoforms are generated by alternative splicing at exons 7–9 (BC and C isoforms) and exon 13 (CYT-1 and CYT-2 isoforms) giving rise to BC1, BC2, C1 and C2. We developed a novel real-time PC...

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Detalles Bibliográficos
Autores principales: Hansen, Aida S., Bundgaard, Bettina B., Møller, Bjarne K., Höllsberg, Per
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064401/
https://www.ncbi.nlm.nih.gov/pubmed/27739531
http://dx.doi.org/10.1038/srep35406