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miR-140-5p attenuates chemotherapeutic drug-induced cell death by regulating autophagy through inositol 1,4,5-trisphosphate kinase 2 (IP3k2) in human osteosarcoma cells

Acquisition of drug-resistant phenotypes is often associated with chemotherapy in osteosarcoma. A number of studies have demonstrated a critical role for autophagy in osteosarcoma development, therapy and drug resistance. However, the molecular mechanisms underlying the autophagy-mediated chemothera...

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Detalles Bibliográficos
Autores principales: Wei, Renxiong, Cao, Gang, Deng, Zhouming, Su, Jiajia, Cai, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064456/
https://www.ncbi.nlm.nih.gov/pubmed/27582507
http://dx.doi.org/10.1042/BSR20160238