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Tilting and Tumbling in Transmembrane Anion Carriers: Activity Tuning through n‐Alkyl Substitution

Anion transport by synthetic carriers (anionophores) holds promise for medical applications, especially the treatment of cystic fibrosis. Among the factors which determine carrier activity, the size and disposition of alkyl groups is proving remarkably important. Herein we describe a series of dithi...

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Detalles Bibliográficos
Autores principales: Edwards, Sophie J., Marques, Igor, Dias, Christopher M., Tromans, Robert A., Lees, Nicholas R., Félix, Vítor, Valkenier, Hennie, Davis, Anthony P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064602/
https://www.ncbi.nlm.nih.gov/pubmed/26748870
http://dx.doi.org/10.1002/chem.201504057