Saturation monitoring of VX15/2503, a novel semaphorin 4D‐specific antibody, in clinical trials

BACKGROUND: Receptor occupancy, or saturation, assays are often utilized in preclinical and clinical development programs to evaluate the binding of a biologic to a cellular target. These assays provide critical information regarding the dose of drug required to “saturate” the target as well as impo...

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Detalles Bibliográficos
Autores principales: Fisher, Terrence L., Seils, Jennifer, Reilly, Christine, Litwin, Virginia, Green, Lisa, Salkowitz‐Bokal, Janelle, Walsh, Robin, Harville, Sarah, Leonard, John E., Smith, Ernest, Zauderer, Maurice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064733/
https://www.ncbi.nlm.nih.gov/pubmed/26566052
http://dx.doi.org/10.1002/cyto.b.21338

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064733/
https://www.ncbi.nlm.nih.gov/pubmed/26566052
http://dx.doi.org/10.1002/cyto.b.21338

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