Cargando…
Saturation monitoring of VX15/2503, a novel semaphorin 4D‐specific antibody, in clinical trials
BACKGROUND: Receptor occupancy, or saturation, assays are often utilized in preclinical and clinical development programs to evaluate the binding of a biologic to a cellular target. These assays provide critical information regarding the dose of drug required to “saturate” the target as well as impo...
| Autores principales: | , , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2015
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064733/ https://www.ncbi.nlm.nih.gov/pubmed/26566052 http://dx.doi.org/10.1002/cyto.b.21338 |