The PtdIns3‐phosphatase MTMR3 interacts with mTORC1 and suppresses its activity

Macroautophagy is a major intracellular degradation system. We previously reported that overexpression of phosphatase‐deficient MTMR3, a member of the myotubularin phosphatidylinositol (PI) 3‐phosphatase family, leads to induction of autophagy. In this study, we found that MTMR3 interacted with mTOR...

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Detalles Bibliográficos
Autores principales: Hao, Feike, Itoh, Takashi, Morita, Eiji, Shirahama‐Noda, Kanae, Yoshimori, Tamotsu, Noda, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Research Letters
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064752/
https://www.ncbi.nlm.nih.gov/pubmed/26787466
http://dx.doi.org/10.1002/1873-3468.12048

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064752/
https://www.ncbi.nlm.nih.gov/pubmed/26787466
http://dx.doi.org/10.1002/1873-3468.12048

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