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Rapid phenotyping of knockout mice to identify genetic determinants of bone strength

The genetic determinants of osteoporosis remain poorly understood, and there is a large unmet need for new treatments in our ageing society. Thus, new approaches for gene discovery in skeletal disease are required to complement the current genome-wide association studies in human populations. The In...

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Detalles Bibliográficos
Autores principales: Freudenthal, Bernard, Logan, John, Croucher, Peter I, Williams, Graham R, Bassett, J H Duncan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064764/
https://www.ncbi.nlm.nih.gov/pubmed/27535945
http://dx.doi.org/10.1530/JOE-16-0258