Cargando…
Rapid phenotyping of knockout mice to identify genetic determinants of bone strength
The genetic determinants of osteoporosis remain poorly understood, and there is a large unmet need for new treatments in our ageing society. Thus, new approaches for gene discovery in skeletal disease are required to complement the current genome-wide association studies in human populations. The In...
Autores principales: | Freudenthal, Bernard, Logan, John, Croucher, Peter I, Williams, Graham R, Bassett, J H Duncan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bioscientifica Ltd
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064764/ https://www.ncbi.nlm.nih.gov/pubmed/27535945 http://dx.doi.org/10.1530/JOE-16-0258 |
Ejemplares similares
-
Rapid-Throughput Skeletal Phenotyping of 100 Knockout Mice Identifies 9 New Genes That Determine Bone Strength
por: Bassett, J. H. Duncan, et al.
Publicado: (2012) -
PYY is a negative regulator of bone mass and strength
por: Leitch, Victoria D., et al.
Publicado: (2019) -
Slc20a2, Encoding the Phosphate Transporter PiT2, Is an Important Genetic Determinant of Bone Quality and Strength
por: Beck‐Cormier, Sarah, et al.
Publicado: (2019) -
Genetically Determined Phenotype Covariation Networks Control Bone Strength
por: Jepsen, Karl J, et al.
Publicado: (2010) -
Systems genetics in diversity outbred mice inform BMD GWAS and identify determinants of bone strength
por: Al-Barghouthi, Basel M., et al.
Publicado: (2021)