Glucocorticoids and 11β-HSD1 are major regulators of intramyocellular protein metabolism

The adverse metabolic effects of prescribed and endogenous glucocorticoid excess, ‘Cushing’s syndrome’, create a significant health burden. While skeletal muscle atrophy and resultant myopathy is a clinical feature, the molecular mechanisms underpinning these changes are not fully defined. We have c...

Descripción completa

Detalles Bibliográficos
Autores principales: Morgan, Stuart A, Hassan-Smith, Zaki K, Doig, Craig L, Sherlock, Mark, Stewart, Paul M, Lavery, Gareth G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064767/
https://www.ncbi.nlm.nih.gov/pubmed/27048233
http://dx.doi.org/10.1530/JOE-16-0011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064767/
https://www.ncbi.nlm.nih.gov/pubmed/27048233
http://dx.doi.org/10.1530/JOE-16-0011

Ejemplares similares