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Glucocorticoids and 11β-HSD1 are major regulators of intramyocellular protein metabolism
The adverse metabolic effects of prescribed and endogenous glucocorticoid excess, ‘Cushing’s syndrome’, create a significant health burden. While skeletal muscle atrophy and resultant myopathy is a clinical feature, the molecular mechanisms underpinning these changes are not fully defined. We have c...
Autores principales: | Morgan, Stuart A, Hassan-Smith, Zaki K, Doig, Craig L, Sherlock, Mark, Stewart, Paul M, Lavery, Gareth G |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bioscientifica Ltd
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064767/ https://www.ncbi.nlm.nih.gov/pubmed/27048233 http://dx.doi.org/10.1530/JOE-16-0011 |
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