PD-L1 is upregulated by EBV-driven LMP1 through NF-κB pathway and correlates with poor prognosis in natural killer/T-cell lymphoma

BACKGROUND: Natural killer/T-cell lymphoma (NKTCL) is an Epstein–Barr virus (EBV)-associated, highly aggressive lymphoma. Treatment outcome remains sub-optimal, especially for advanced-stage or relapsed diseases. Programmed cell death receptor 1 (PD-1) and PD ligand 1 (PD-L1) have become promising t...

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Detalles Bibliográficos
Autores principales: Bi, Xi-wen, Wang, Hua, Zhang, Wen-wen, Wang, Jing-hua, Liu, Wen-jian, Xia, Zhong-jun, Huang, Hui-qiang, Jiang, Wen-qi, Zhang, Yu-jing, Wang, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064887/
https://www.ncbi.nlm.nih.gov/pubmed/27737703
http://dx.doi.org/10.1186/s13045-016-0341-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064887/
https://www.ncbi.nlm.nih.gov/pubmed/27737703
http://dx.doi.org/10.1186/s13045-016-0341-7

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