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PD-L1 is upregulated by EBV-driven LMP1 through NF-κB pathway and correlates with poor prognosis in natural killer/T-cell lymphoma

BACKGROUND: Natural killer/T-cell lymphoma (NKTCL) is an Epstein–Barr virus (EBV)-associated, highly aggressive lymphoma. Treatment outcome remains sub-optimal, especially for advanced-stage or relapsed diseases. Programmed cell death receptor 1 (PD-1) and PD ligand 1 (PD-L1) have become promising t...

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Detalles Bibliográficos
Autores principales:	Bi, Xi-wen, Wang, Hua, Zhang, Wen-wen, Wang, Jing-hua, Liu, Wen-jian, Xia, Zhong-jun, Huang, Hui-qiang, Jiang, Wen-qi, Zhang, Yu-jing, Wang, Liang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064887/ https://www.ncbi.nlm.nih.gov/pubmed/27737703 http://dx.doi.org/10.1186/s13045-016-0341-7

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