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Genetic and Biochemical Approaches for In Vivo and In Vitro Assessment of Protein Oligomerization: The Ryanodine Receptor Case Study

Oligomerization is often a structural requirement for proteins to accomplish their specific cellular function. For instance, tetramerization of the ryanodine receptor (RyR) is necessary for the formation of a functional Ca(2+) release channel pore. Here, we describe detailed protocols for the assess...

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Detalles Bibliográficos
Autores principales: Stanczyk, Paulina J., Lai, F. Anthony, Zissimopoulos, Spyros
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MyJove Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065051/
https://www.ncbi.nlm.nih.gov/pubmed/27500320
http://dx.doi.org/10.3791/54271