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The mitogen and stress-activated protein kinase 1 regulates the rapid epigenetic tagging of dorsal horn neurons and nocifensive behaviour
Phosphorylation of histone H3 at serine 10 (p-H3S10) is a marker of active gene transcription. Using cognitive models of neural plasticity, p-H3S10 was shown to be downstream of extracellular signal-regulated kinase (ERK) signalling in the hippocampus. In this study, we show that nociceptive signall...
Autores principales: | Tochiki, Keri K., Maiarú, Maria, Norris, Caspar, Hunt, Stephen P., Géranton, Sandrine M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065054/ https://www.ncbi.nlm.nih.gov/pubmed/27482631 http://dx.doi.org/10.1097/j.pain.0000000000000679 |
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