Achieving a physiological cortisol profile with once-daily dual-release hydrocortisone: a pharmacokinetic study

OBJECTIVE: Oral once-daily dual-release hydrocortisone (DR-HC) replacement therapy was developed to provide a cortisol exposure−time profile that closely resembles the physiological cortisol profile. This study aimed to characterize single-dose pharmacokinetics (PK) of DR-HC 5–20mg and assess intras...

Descripción completa

Detalles Bibliográficos
Autores principales: Johannsson, Gudmundur, Lennernäs, Hans, Marelli, Claudio, Rockich, Kevin, Skrtic, Stanko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2016
Materias:
Clinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065076/
https://www.ncbi.nlm.nih.gov/pubmed/27129362
http://dx.doi.org/10.1530/EJE-15-1212

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065076/
https://www.ncbi.nlm.nih.gov/pubmed/27129362
http://dx.doi.org/10.1530/EJE-15-1212

Ejemplares similares