Zfp423 Regulates Sonic Hedgehog Signaling via Primary Cilium Function

Zfp423 encodes a 30-zinc finger transcription factor that intersects several canonical signaling pathways. Zfp423 mutations result in ciliopathy-related phenotypes, including agenesis of the cerebellar vermis in mice and Joubert syndrome (JBTS19) and nephronophthisis (NPHP14) in humans. Unlike most...

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Detalles Bibliográficos
Autores principales: Hong, Chen-Jei, Hamilton, Bruce A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065120/
https://www.ncbi.nlm.nih.gov/pubmed/27727273
http://dx.doi.org/10.1371/journal.pgen.1006357

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065120/
https://www.ncbi.nlm.nih.gov/pubmed/27727273
http://dx.doi.org/10.1371/journal.pgen.1006357

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