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Zfp423 Regulates Sonic Hedgehog Signaling via Primary Cilium Function

Zfp423 encodes a 30-zinc finger transcription factor that intersects several canonical signaling pathways. Zfp423 mutations result in ciliopathy-related phenotypes, including agenesis of the cerebellar vermis in mice and Joubert syndrome (JBTS19) and nephronophthisis (NPHP14) in humans. Unlike most...

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Detalles Bibliográficos
Autores principales:	Hong, Chen-Jei, Hamilton, Bruce A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065120/ https://www.ncbi.nlm.nih.gov/pubmed/27727273 http://dx.doi.org/10.1371/journal.pgen.1006357

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