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High-Throughput Identification of Adaptive Mutations in Experimentally Evolved Yeast Populations
High-throughput sequencing has enabled genetic screens that can rapidly identify mutations that occur during experimental evolution. The presence of a mutation in an evolved lineage does not, however, constitute proof that the mutation is adaptive, given the well-known and widespread phenomenon of g...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065121/ https://www.ncbi.nlm.nih.gov/pubmed/27727276 http://dx.doi.org/10.1371/journal.pgen.1006339 |