Directed Evolution Reveals Unexpected Epistatic Interactions That Alter Metabolic Regulation and Enable Anaerobic Xylose Use by Saccharomyces cerevisiae

The inability of native Saccharomyces cerevisiae to convert xylose from plant biomass into biofuels remains a major challenge for the production of renewable bioenergy. Despite extensive knowledge of the regulatory networks controlling carbon metabolism in yeast, little is known about how to reprogr...

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Detalles Bibliográficos
Autores principales: Sato, Trey K., Tremaine, Mary, Parreiras, Lucas S., Hebert, Alexander S., Myers, Kevin S., Higbee, Alan J., Sardi, Maria, McIlwain, Sean J., Ong, Irene M., Breuer, Rebecca J., Avanasi Narasimhan, Ragothaman, McGee, Mick A., Dickinson, Quinn, La Reau, Alex, Xie, Dan, Tian, Mingyuan, Reed, Jennifer L., Zhang, Yaoping, Coon, Joshua J., Hittinger, Chris Todd, Gasch, Audrey P., Landick, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065143/
https://www.ncbi.nlm.nih.gov/pubmed/27741250
http://dx.doi.org/10.1371/journal.pgen.1006372

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065143/
https://www.ncbi.nlm.nih.gov/pubmed/27741250
http://dx.doi.org/10.1371/journal.pgen.1006372

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