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Robust Therapeutic Efficacy of Matrix Metalloproteinase-2-Cleavable Fas-1-RGD Peptide Complex in Chronic Inflammatory Arthritis

OBJECTIVE: Therapeutic agents that are transformable via introducing cleavable linkage by locally enriched MMP-2 within inflamed synovium would enhance therapeutic efficacy on chronic inflammatory arthritis. Transforming growth factor-β-inducible gene-h3 (βig-h3), which consists of four fas-1 domain...

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Detalles Bibliográficos
Autores principales: Nam, Eon Jeong, Kang, Jin Hee, Sa, Keum Hee, Sung, Shijin, Park, Jae Yong, Jo, Dong-Gyu, Park, Jae Hyung, Kim, In San, Kang, Young Mo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065154/
https://www.ncbi.nlm.nih.gov/pubmed/27741237
http://dx.doi.org/10.1371/journal.pone.0164102