Mechanistic Modelling and Bayesian Inference Elucidates the Variable Dynamics of Double-Strand Break Repair

DNA double-strand breaks are lesions that form during metabolism, DNA replication and exposure to mutagens. When a double-strand break occurs one of a number of repair mechanisms is recruited, all of which have differing propensities for mutational events. Despite DNA repair being of crucial importa...

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Detalles Bibliográficos
Autores principales: Woods, Mae L., Barnes, Chris P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065155/
https://www.ncbi.nlm.nih.gov/pubmed/27741226
http://dx.doi.org/10.1371/journal.pcbi.1005131

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065155/
https://www.ncbi.nlm.nih.gov/pubmed/27741226
http://dx.doi.org/10.1371/journal.pcbi.1005131

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