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Mechanistic Insights into Archaeal and Human Argonaute Substrate Binding and Cleavage Properties
Argonaute (Ago) proteins from all three domains of life are key players in processes that specifically regulate cellular nucleic acid levels. Some of these Ago proteins, among them human Argonaute2 (hAgo2) and Ago from the archaeal organism Methanocaldococcus jannaschii (MjAgo), are able to cleave n...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065165/ https://www.ncbi.nlm.nih.gov/pubmed/27741323 http://dx.doi.org/10.1371/journal.pone.0164695 |