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Corticosteroids Mediate Heart Failure-Induced Depression through Reduced σ1-Receptor Expression
Cardiovascular diseases are risk factors for depression in humans. We recently proposed that σ(1) receptor (σ(1)R) stimulation rescued cardiac hypertrophy and heart failure induced by transverse aortic constriction (TAC) in mice. Importantly, σ(1)R stimulation reportedly ameliorates depression-like...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065174/ https://www.ncbi.nlm.nih.gov/pubmed/27741227 http://dx.doi.org/10.1371/journal.pone.0163992 |